abstract：:Frugivorous and nectarivorous bats rely largely on hepatic glycogenesis and glycogenolysis for postprandial blood glucose disposal and maintenance of glucose homeostasis during short time starvation, respectively. The glycogen synthase 2 encoded by the Gys2 gene plays a critical role in liver glycogen synthesis. To te...

journal_title：Journal of molecular evolution

authors： Qian Y,Fang T,Shen B,Zhang S

更新日期：2014-01-01 00:00:00

abstract：:MicroRNAs (miRNAs) are small noncoding RNA molecules which are processed into ~20-24 nt molecules that can regulate the gene expression post-transcriptionally. MiRNA gene clusters have been identified in a range of species, where in miRNAs are often processed from polycistronic transcripts. In this study, a computatio...

journal_title：Journal of molecular evolution

authors： de Souza Gomes M,Donoghue MT,Muniyappa M,Pereira RV,Guerra-Sá R,Spillane C

更新日期：2013-06-01 00:00:00

abstract：:There has been considerable discussion in recent years on the evolution of the tandemly repeated multigene families, since some organisms show a concerted model whereas others show a birth-and-death model. This controversial subject extends to several species of fish. In this study, three species of the Sparidae famil...

journal_title：Journal of molecular evolution

authors： Merlo MA,Cross I,Manchado M,Cárdenas S,Rebordinos L

更新日期：2013-03-01 00:00:00

abstract：:Nucleotide polymorphisms in two North American balsam poplars (Populus trichocarpa Torr. & Gray and P. balsamifera L.; section Tacamahaca), and one Eurasian aspen (P. tremula L.; section Populus) were compared using nine loci involved in defense, stress response, photoperiodism, freezing tolerance, and housekeeping. N...

journal_title：Journal of molecular evolution

authors： Ismail M,Soolanayakanahally RY,Ingvarsson PK,Guy RD,Jansson S,Silim SN,El-Kassaby YA

更新日期：2012-06-01 00:00:00

abstract：:Mutational bias toward expansion or contraction of simple sequence repeats (SSRs) is referred to as directionality of SSR evolution. In this communication, we report the mutational bias exhibited by mononucleotide SSRs occurring in the non-coding regions of several prokaryotic genomes. Our investigations revealed that...

journal_title：Journal of molecular evolution

authors： Kumar P,Nagarajaram HA

更新日期：2012-04-01 00:00:00

abstract：:Spermatogenesis is one of the most complex biological processes undergone by any organism, making it susceptible to perturbations that result in male sterility. Research has demonstrated that mutant phenotypes can be obtained from the disruption of epigenetic modifications, which are commonly microRNA guided. Employin...

journal_title：Journal of molecular evolution

authors： Madison-Villar MJ,Michalak P

更新日期：2011-12-01 00:00:00

abstract：:The NF-κB family of transcription factors is activated in response to many environmental and biological stresses, and plays a key role in innate immunity across a broad evolutionary expanse of animals. A simple NF-κB pathway is present in the sea anemone Nematostella vectensis, an important model organism in the phylu...

journal_title：Journal of molecular evolution

authors： Wolenski FS,Chandani S,Stefanik DJ,Jiang N,Chu E,Finnerty JR,Gilmore TD

更新日期：2011-12-01 00:00:00

abstract：:We provide here evidence for a conserved regulatory element for transcription of the β-family globin genes based on a comparative study of 32 genes from 16 mammals. The element is characterized by the appearance of AA or TT dinucleotides in the A + T-rich region located 200-400 bp upstream of the cap sites. G-tracts 3...

journal_title：Journal of molecular evolution

authors： Kiyama R,Wada-Kiyama Y

更新日期：2011-10-01 00:00:00

abstract：:Evidence from a number of studies indicates that protein folding is dictated not only by factors stabilizing the native state, but also by potentially independent factors that create folding pathways. How natural selection might cope simultaneously with two independent factors was addressed in this study within the fr...

journal_title：Journal of molecular evolution

authors： Lee SY,Parker W

更新日期：2011-10-01 00:00:00

abstract：:The recent availability of genome sequences of four different Fusarium species offers the opportunity to perform extensive comparative analyses, in particular of repeated sequences. In a recent work, the overall content of such sequences in the genomes of three phylogenetically related Fusarium species, F. graminearum...

journal_title：Journal of molecular evolution

authors： Dufresne M,Lespinet O,Daboussi MJ,Hua-Van A

更新日期：2011-10-01 00:00:00

abstract：:The diversity of functional genes and the related processes are important issues for conservation biology. This is especially relevant for populations that have suffered from demographic reduction as a consequence of the processes of postglacial colonization. In this perspective, the aims of the present study are (1) ...

journal_title：Journal of molecular evolution

authors： Girard P,Angers B

更新日期：2011-08-01 00:00:00

abstract：:The study of genetic evolution within the context of adaptive radiations offers insights to genes and selection pressures that result in rapid morphological change. Cichlid fishes are very species-rich and variable in coloration, behavior, and morphology, and so provide a classical model system for studying the geneti...

journal_title：Journal of molecular evolution

authors： Fan S,Elmer KR,Meyer A

更新日期：2011-08-01 00:00:00

abstract：:Examination of the mitochondrial small subunit ribosomal RNA (rns) gene of five species of the fungal genus Leptographium revealed that the gene has been invaded at least once at position 952 by a group II intron encoding a LAGLIDADG homing endonuclease gene. Phylogenetic analyses of the intron and homing endonuclease...

journal_title：Journal of molecular evolution

authors： Mullineux ST,Willows K,Hausner G

更新日期：2011-06-01 00:00:00

abstract：:Hydrophobins are small proteins, characterised by the presence of eight positionally conserved cysteine residues, and are present in all filamentous asco- and basidiomycetes. They are found on the outer surfaces of cell walls of hyphae and conidia, where they mediate interactions between the fungus and the environment...

journal_title：Journal of molecular evolution

authors： Seidl-Seiboth V,Gruber S,Sezerman U,Schwecke T,Albayrak A,Neuhof T,von Döhren H,Baker SE,Kubicek CP

更新日期：2011-04-01 00:00:00

abstract：:DEAD-box proteins are found in all domains of life and participate in almost all cellular processes that involve RNA. The presence of DEAD and Helicase_C conserved domains distinguish these proteins. DEAD-box proteins exhibit RNA-dependent ATPase activity in vitro, and several also show RNA helicase activity. In this ...

journal_title：Journal of molecular evolution

authors： López-Ramírez V,Alcaraz LD,Moreno-Hagelsieb G,Olmedo-Álvarez G

更新日期：2011-04-01 00:00:00

abstract：:Throughout history, remote archipelagos have repeatedly been designated natural laboratories to study evolutionary processes. The extensive, geographically structured, morphological variation within Galápagos' Opuntia cacti has been presumed to be another example of how such processes shape diversity. However, recent ...

journal_title：Journal of molecular evolution

authors： Helsen P,Verdyck P,Van Dongen S

更新日期：2011-03-01 00:00:00

abstract：:Copia is a retrotransposon that appears to be distributed widely among the Drosophilidae subfamily. Evolutionary analyses of regulatory regions have indicated that the Copia retrotransposon evolved through both positive and purifying selection, and that horizontal transfer (HT) could also explain its patchy distributi...

journal_title：Journal of molecular evolution

authors： de Setta N,Van Sluys MA,Capy P,Carareto CM

更新日期：2011-03-01 00:00:00

abstract：:Analysis of occurrence of simple amino acid repeats in large ensemble of prokaryotic and eukaryotic sequences reveals that nearly all amino acids found in the repeats belong to those which have in their codon repertoires aggressively expanding triplets, all of three known pathologically expanding classes GCU (GCU, CUG...

journal_title：Journal of molecular evolution

authors： Koren Z,Trifonov EN

更新日期：2011-02-01 00:00:00

abstract：:Male sex genes have shown a pattern of rapid interspecies divergence at both the coding and gene expression level. A common outcome from crosses between closely-related species is hybrid male sterility. Phenotypic and genetic studies in Drosophila sterile hybrid males have shown that spermatogenesis arrest is postmeio...

journal_title：Journal of molecular evolution

authors： Sundararajan V,Civetta A

更新日期：2011-01-01 00:00:00

abstract：:The relaxin (RLN) and insulin-like (INSL) gene family is a group of genes involved in a variety of physiological roles that includes bone formation, testicular descent, trophoblast development, and cell differentiation. This family appears to have expanded in vertebrates relative to non-vertebrate chordates, but the r...

journal_title：Journal of molecular evolution

authors： Hoffmann FG,Opazo JC

更新日期：2011-01-01 00:00:00

abstract：:The evolutionary speed and the consequent immune escape of H3N2 influenza A virus make it an interesting evolutionary system. Charged amino acid residues are often significant contributors to the free energy of binding for protein-protein interactions, including antibody-antigen binding and ligand-receptor binding. We...

journal_title：Journal of molecular evolution

authors： Pan K,Long J,Sun H,Tobin GJ,Nara PL,Deem MW

更新日期：2011-01-01 00:00:00

abstract：:Microsporidia are a group of obligate intracellular eukaryotic parasites with small genomes. They infect animals from a wide variety of phyla, including humans. Two manganese superoxide dismutase (MnSOD) genes, designated NbMnSOD1 and NbMnSOD2, were found to be organized in a tandem array within the Nosema bombycis ge...

journal_title：Journal of molecular evolution

authors： Xiang H,Pan G,Vossbrinck CR,Zhang R,Xu J,Li T,Zhou Z,Lu C,Xiang Z

更新日期：2010-12-01 00:00:00

abstract：:Species identification is one of the most important issues in biological studies. Due to recent increases in the amount of genomic information available and the development of DNA sequencing technologies, the applicability of using DNA sequences to identify species (commonly referred to as "DNA barcoding") is being te...

journal_title：Journal of molecular evolution

authors： Seo TK

更新日期：2010-10-01 00:00:00

abstract：:The RpoS sigma factor in proteobacteria regulates genes in stationary phase and in response to stress. Although of conserved function, the RpoS regulon may have different gene composition across species due to high genomic diversity and to known environmental conditions that select for RpoS mutants. In this study, the...

journal_title：Journal of molecular evolution

authors： Chiang SM,Schellhorn HE

更新日期：2010-06-01 00:00:00

abstract：:Natural populations of the Midas cichlid species in several different crater lakes in Nicaragua exhibit a conspicuous color polymorphism. Most individuals are dark and the remaining have a gold coloration. The color morphs mate assortatively and sympatric population differentiation has been shown based on neutral mole...

journal_title：Journal of molecular evolution

authors： Henning F,Renz AJ,Fukamachi S,Meyer A

更新日期：2010-05-01 00:00:00

abstract：:Liverworts are well supported as the sister group to all other land plants (embryophytes) by molecular data. Observations strongly supporting this earliest dichotomy in embryophyte evolution are the strikingly different introns occurring in the mitochondrial DNAs of liverworts versus non-liverwort embryophytes (NLE), ...

journal_title：Journal of molecular evolution

authors： Volkmar U,Knoop V

更新日期：2010-05-01 00:00:00

abstract：:Bacterial lipoproteins, characterized by the N-terminal N-acyl S-diacylglyceryl Cysteine, are key membrane proteins in bacterial homeostasis. It is generally thought that during the modification lipoprotein precursors are translocated via the Sec-machinery in an unfolded state. The recent discovery of twin-arginine tr...

journal_title：Journal of molecular evolution

authors： Shruthi H,Babu MM,Sankaran K

更新日期：2010-04-01 00:00:00

abstract：:The question of whether natural selection favors genetic stability or genetic variability is a fundamental problem in evolutionary biology. Bioinformatic analyses demonstrate that selection favors genetic stability by avoiding unstable nucleotide sequences in protein encoding DNA. Yet, such unstable sequences are main...

journal_title：Journal of molecular evolution

authors： Falster DS,Nakken S,Bergem-Ohr M,Rødland EA,Breivik J

更新日期：2010-03-01 00:00:00

abstract：:The PIGSFEAST (PF) exon of the Drosophila dumpy gene is undergoing concerted evolution by the process of unequal crossing over. We have developed a long-range PCR-based assay to amplify the approximately 12 kb long exon which contains variable numbers of 303 or 306 nt long repeats in a tandem array. We applied this pr...

journal_title：Journal of molecular evolution

authors： Carmon A,Larson M,Wayne M,MacIntyre R

更新日期：2010-03-01 00:00:00

abstract：:Previous studies have revealed a major difference in the phylogenetic structure, extent of genetic diversity, and selection pressure between the surface glycoproteins and internal gene segments of avian influenza viruses (AIV) sampled from wild birds. However, what evolutionary processes are responsible for these stri...

journal_title：Journal of molecular evolution

authors： Chen R,Holmes EC

更新日期：2010-01-01 00:00:00

abstract：:Energised by the protonmotive force and with the intervention of inorganic catalysts, at base Life reacts hydrogen from a variety of sources with atmospheric carbon dioxide. It seems inescapable that life emerged to fulfil the same role (i.e., to hydrogenate CO(2)) on the early Earth, thus outcompeting the slow geoche...

journal_title：Journal of molecular evolution

authors： Nitschke W,Russell MJ

更新日期：2009-11-01 00:00:00

abstract：:The codon assignment of the quasi-universal genetic code can be assumed to have resulted from the evolutionary pressures that prevailed when the code was still evolving. Here, we review studies of the structure of the genetic code based on optimization models. We also review studies that, from the structure of the cod...

journal_title：Journal of molecular evolution

authors： Jestin JL,Kempf A

更新日期：2009-11-01 00:00:00

abstract：:Life is based on biopolymers that have the ability to replicate themselves. Here we consider how a self-replicating RNA system may have originated. We consider a reaction system in which polymerization is possible by the addition of an activated monomer to the end of a chain. We suppose that a small fraction of polyme...

journal_title：Journal of molecular evolution

authors： Wu M,Higgs PG

更新日期：2009-11-01 00:00:00

abstract：:We investigated the molecular evolution of duplicated color vision genes (LWS-1 and SWS2) within cyprinid fish, focusing on the most cavefish-rich genus--Sinocyclocheilus. Maximum likelihood-based codon substitution approaches were used to analyze the evolution of vision genes. We found that the duplicated color visio...

journal_title：Journal of molecular evolution

authors： Li Z,Gan X,He S

更新日期：2009-10-01 00:00:00

abstract：:Synechococcus and Prochlorococcus have made great contributions to earth's photosynthetic biomass. ATP-binding cassette (ABC) protein systems have been characterized to play important roles in various physiological functions, including carbon fixation, phosphate assimilation, and vitamin B(12) metabolism. In this stud...

journal_title：Journal of molecular evolution

authors： Bu L,Xiao J,Lu L,Xu G,Li J,Zhao F,Li X,Wu J

更新日期：2009-10-01 00:00:00

abstract：:Here we analyze the molecular evolution of the beta-esterase gene cluster in the Drosophila genus using the recently released genome sequences of 12 Drosophila species. Molecular evolution in this small cluster is noteworthy because it contains contrasting examples of the types and stages of loss of gene function. Spe...

journal_title：Journal of molecular evolution

authors： Robin C,Bardsley LM,Coppin C,Oakeshott JG

更新日期：2009-07-01 00:00:00

abstract：:The metabolic cycle of Saccharomyces cerevisiae consists of alternating oxidative (respiration) and reductive (glycolysis) energy-yielding reactions. The intracellular concentrations of amino acid precursors generated by these reactions oscillate accordingly, attaining maximal concentration during the middle of their ...

journal_title：Journal of molecular evolution

authors： de Bivort BL,Perlstein EO,Kunes S,Schreiber SL

更新日期：2009-05-01 00:00:00

abstract：:The mammalian olfactory system utilizes three large receptor families: the olfactory receptors (ORs) of the main nose and the vomeronasal type-1 and type-2 receptor genes (V1Rs and V2Rs) of the vomeronasal organ. We find that these loci are among the most long interspersed nuclear element (LINE)-dense regions of mamma...

journal_title：Journal of molecular evolution

authors： Kambere MB,Lane RP

更新日期：2009-02-01 00:00:00

abstract：:Compared with the X chromosome, the mammalian Y chromosome is considerably diminished in size and has lost most of its ancestral genes during evolution. Interestingly, for the X-degenerate region on the Y chromosome, human has retained all 16 genes, while chimpanzee has lost 4 of the 16 genes since the divergence of t...

journal_title：Journal of molecular evolution

authors： Goto H,Peng L,Makova KD

更新日期：2009-02-01 00:00:00

abstract：:The homeobox gene Hoxa-13 codes for a transcription factor involved in multiple functions, including body axis and hand/foot development in tetrapods. In this study we investigate whether the loss of one function (e.g., limb loss in snakes) left a molecular footprint in exon 1 of Hoxa-13 that could be associated with ...

journal_title：Journal of molecular evolution

authors： Kohlsdorf T,Cummings MP,Lynch VJ,Stopper GF,Takahashi K,Wagner GP

更新日期：2008-12-01 00:00:00